Medicinal Mushrooms for Menopause: Powerful Natural Support for Brain, Skin, and Hormonal Health
- Amanda Prince

- Jul 20
- 3 min read

The menopause journey is a time of transformation, not just hormonally, but also mentally, emotionally, and physically. While HRT can be life-changing for many, there's growing interest in natural ways to support wellbeing during this transition.
This article does not advocate stopping HRT which is MHRA regulated and evidence backed to improve cardiovascular and bone health during menopause. We are exploring the possibility of additional support and holistic remedies for those choosing not to take HRT or who may be unable to do so.
Medicinal mushrooms: Used for centuries in Eastern medicine, functional mushrooms are now gaining global recognition for their ability to boost immunity, support the brain, enhance energy, and even nourish the skin, all of which are particularly relevant for menopausal women.
What Are Medicinal Mushrooms?
Medicinal mushrooms are a class of fungi that contain bioactive compounds like polysaccharides (especially beta-glucans), triterpenes, and antioxidants. These compounds have been shown to:
Support immune function
Reduce inflammation
Improve cognition and mood
Support hormonal balance indirectly
Protect against oxidative stress and ageing
Rather than acting as stimulants or hormone mimics, medicinal mushrooms help the body maintain balance, making them ideal allies for women seeking holistic support during menopause.
Top Medicinal Mushrooms for Menopausal Women
Here’s a closer look at some of the most well-researched and popular mushrooms for health and longevity, especially for women over 40:
Mushroom | Benefits | Menopause-Specific Support | Research Highlights |
Lion’s Mane (Hericium erinaceus) | Neuroprotective, improves focus and memory, supports nerve regeneration | Helpful for brain fog, mood swings, and memory | A 2009 study showed improved cognitive function in older adults; may support mood regulation through NGF stimulation |
Tremella (Tremella fuciformis) | Skin hydration, collagen support, anti-ageing | Promotes skin elasticity and reduces dryness (common in menopause) | Contains polysaccharides that rival hyaluronic acid in moisture retention |
Reishi (Ganoderma lucidum) | Calms the nervous system, supports sleep, boosts immunity | Helps with anxiety, insomnia, and stress resilience | Traditionally called the “mushroom of immortality”; supports parasympathetic nervous system |
Chaga (Inonotus obliquus) | Antioxidant powerhouse, supports immunity and reduces inflammation | May protect against cellular ageing and oxidative stress | Rich in melanin and superoxide dismutase, supports skin and gut health |
Cordyceps (Cordyceps militaris/sinensis) | Increases energy and oxygen uptake, supports libido and stamina | Ideal for fatigue, low motivation, or reduced sexual drive | May enhance physical performance and mitochondrial function in older adults |
Shiitake (Lentinula edodes) | Immune modulator, supports heart and metabolic health | Helps counter weight gain and inflammation linked to menopause | Contains lentinan, a beta-glucan that enhances immune function and cholesterol balance |
Why Mushrooms Work So Well for Midlife Health
As women move through menopause, they face a range of interconnected symptoms — from disrupted sleep and mood to ageing skin and hormonal weight gain. Medicinal mushrooms offer a multi-system benefit:
Nervous system: Lion’s Mane and Reishi calm the mind and support cognition
Immune system: Shiitake, Chaga, and Cordyceps strengthen immunity and reduce inflammation
Skin and ageing: Tremella and Chaga may enhance collagen, hydration, and antioxidant defence
Hormonal stress: Reishi and Cordyceps help manage cortisol and energy levels naturally
Unlike synthetic supplements, mushrooms support the body’s own intelligence, helping restore resilience and balance.
Are Medicinal Mushrooms Safe?
Generally, yes, especially when taken from reputable, organic sources. However, a few important notes:
Consult a clinician if you’re on medications (especially immunosuppressants or anticoagulants)
Avoid combining with high-dose hormone supplements unless advised
Introduce one at a time to observe effects taking regularly rather than occasionally
Look for dual-extract formulas for maximum bioavailability
The Bottom Line
Medicinal mushrooms offer menopausal women a safe, nourishing way to support brain health, skin vitality, immune strength, and long-term wellness. Whether you’re struggling with low mood, poor sleep, or ageing skin, there’s likely a mushroom that can help.
Get in touch to discuss your Symptoms of menopause, including your health, longevity and well being
Regards
Amanda



