Polynucleotides

What Are Polynucleotides?

As aesthetic medicine moves beyond simply "filling lines," polynucleotide treatments are gaining attention for their ability to regenerate, repair and deeply hydrate the skin from within. Unlike traditional injectables, polynucleotides work by stimulating your body’s own natural healing processes, making them a powerful choice for clients seeking subtle, natural skin improvement without altering facial structure.

Polynucleotides are chains of DNA fragments derived from purified salmon or trout DNA. These molecules are biocompatible and biologically active, meaning they are recognised and well tolerated by human tissue.

When injected into the skin, polynucleotides act as:

• Scavengers of free radicals (reducing oxidative stress)

• Activators of fibroblasts, the cells responsible for producing collagen and elastin

• Hydrators, improving moisture retention and skin elasticity

• Regenerators, supporting tissue repair and microcirculation

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The result is healthier, firmer, more radiant skin—achieved by stimulating your skin to behave like younger skin again.

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How Do They Work?

Polynucleotide injections are administered using a fine needle or cannula, typically into the mid to deep dermis. Once delivered, they:

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• Trigger cellular repair and tissue regeneration

• Improve collagen and elastin synthesis

• Encourage angiogenesis (new blood vessel formation), improving oxygen and nutrient delivery

• Support the skin’s natural barrier and hydration function

This is a regenerative treatment, not a filler—so results develop gradually over a period of weeks as your body responds to the treatment.

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What Are the Benefits?

Polynucleotides offer wide-ranging benefits for skin quality and overall tissue health. They can be used on the face, neck, décolletage, hands, and under-eyes, as well as in delicate or scarred areas.

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Key benefits include:

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• Improved skin tone, elasticity and firmness

• Smoother, more refined texture

• Increased hydration from within

• Reduced fine lines and early wrinkles

• Support for acne scarring, rosacea, or post-treatment skin

• Brightening and firming of under-eye hollows or crepey skin

• General anti-ageing support in both younger and more mature skin

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Who Are Polynucleotides Suitable For?

This treatment is ideal for:

• Clients seeking natural skin rejuvenation

• Those looking to improve crepey, dehydrated, or thin skin

• Individuals wanting to support long-term skin health

• People who prefer subtle results without volume changes

• Those with sensitive skin or concerns such as acne, rosacea or scarring

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Polynucleotides are safe for a wide range of ages and skin types. They can be used alone or alongside other treatments like microneedling, mesotherapy, or skin boosters.

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How Many Sessions Are Needed?

A course of 3 treatments spaced 2–3 weeks apart is typically recommended, followed by maintenance treatments every 6–9 months depending on your skin goals and age.

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Because the results are cumulative and regenerative, clients usually see:

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• Improved glow and texture after the first session

• Firmness and resilience increasing over 4–6 weeks

• Continued improvement in skin tone and hydration for several months

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What to Expect After Treatment

Minimal downtime — some mild redness or swelling at injection sites may occur, resolving within 24–48 hours

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• No significant bruising or irritation for most clients

• Makeup can typically be worn the next day

• Full aftercare guidance is provided

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Prices:

Eyes Area £120
Face and Neck £160